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Association of coronary artery calcium with adverse cardiovascular outcomes and death in patients with chronic kidney disease: results from the KNOW-CKD by Chan-Young Jung; Hae-Ryong Yun; Jung Tak Park; Young Su Joo; Hyung Woo Kim; Tae-Hyun Yoo; Shin-Wook Kang; Joongyub Lee; Dong-Wan Chae; Wookyung Chung; Yong-Soo Kim; Kook-Hwan Oh; Seung Hyeok Han is a Medicine article available to read on EtoBox.
What is Association of coronary artery calcium with adverse cardiovascular outcomes and death in patients with chronic kidney disease: results from the KNOW-CKD about?
## ABSTRACT ## Background In East Asian countries, patients with chronic kidney disease (CKD) have lower cardiovascular risk profiles and experience fewer cardiovascular events (CVEs) than those in Western countries. Thus the clinical predictive performance of well-known risk factors warrants further testing in this population. ## Methods The KoreaN cohort study for Outcome in patients With Chronic Kidney Disease (KNOW-CKD) is a multicenter, prospective observational study. We included 1579 participants with CKD G1–G5 without kidney replacement therapy between 2011 and 2016. The main predictor was the coronary artery calcium score (CACS). The primary outcome was a composite of nonfatal CVEs or all-cause mortality. Secondary outcomes included 3-point major adverse cardiovascular events (MACEs; the composite of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke), all CVEs and all-cause mortality. ## Results During a median follow-up of 5.1 years, a total of 123 primary outcome events occurred (incidence rate 1.6/100 person-years). In the multivariable Cox model, a 1-standard deviation log increase in the CACS was associated with a 1.67-fold [95% confidence inter
Who reads Association of coronary artery calcium with adverse cardiovascular outcomes and death in patients with chronic kidney disease: results from the KNOW-CKD?
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- Author
- Chan-Young Jung; Hae-Ryong Yun; Jung Tak Park; Young Su Joo; Hyung Woo Kim; Tae-Hyun Yoo; Shin-Wook Kang; Joongyub Lee; Dong-Wan Chae; Wookyung Chung; Yong-Soo Kim; Kook-Hwan Oh; Seung Hyeok Han
- Publisher
- Oxford University Press (OUP)
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)