Can I read Chromosomes and Chromatin on EtoBox?

Chromosomes and Chromatin by James R Paulson; Paola Vagnarelli is a book available to read on EtoBox.

What is Chromosomes and Chromatin about?

## Abstract Chromosomes are structures within the nuclei of eukaryotic cells that contain deoxyribonucleic acid (DNA) combined with proteins. Chromatin refers to the material of the chromosomes – DNA plus proteins. Before DNA replication, each chromosome contains a single, very long DNA molecule that basically runs from one end of the chromosome to the other. Core histone proteins package segments of this DNA molecule into nucleosomes, and linker histones further compact the resulting ‘string of beads’ into a 30‐nm chromatin fibre. In mitotic chromosomes, scaffold proteins fold the chromatin fibre into loops along its length. Chromosomes are very dynamic structures and take several forms, but the basic organisation is always related to the structure of mitotic chromosomes. The location of chromosomes in the nucleus, the nature of the loops and modifications to the chromatin fibre are thought to be important in determining which DNA sequences are made available for transcription and other processes. ## Key Concepts: In eukaryotic cells, genes are located in chromosomes in the cell nucleus. Before the DNA has been replicated, a chromosome consists of a single very long DNA double hel

Author

James R Paulson; Paola Vagnarelli

Publisher

John Wiley & Sons Incorporated,

Published

2011

Language

EN

ISBN

9780333947890