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This study presents a novel pH-sensitive dual-release hydrogel made from carboxymethyl chitosan and oxidized sodium alginate, designed for diabetic wound healing. The hydrogel incorporates astilbin liposomes and diclofenac sodium to provide controlled release of therapeutic agents, promoting anti-inflammatory effects, angiogenesis, and wound repair. In vitro and in vivo results indicate that this hydrogel is biocompatible and effectively enhances the healing process of chronic diabetic wounds.

Author

hann48209

Language

EN