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Can I read Traditional Mongolian medicine Eerdun Wurile improves stroke recovery through regulation of gene expression in rat brain on EtoBox?
Traditional Mongolian medicine Eerdun Wurile improves stroke recovery through regulation of gene expression in rat brain by Gaowa, Saren; Bao, Narisi; Da, Man; Qiburi, Qiburi; Ganbold, Tsogzolmaa; Chen, Lu; Altangerel, Altanzul; Temuqile, Temuqile; Baigude, Huricha is a Agricultural and Biological Sciences article available to read on EtoBox.
What is Traditional Mongolian medicine Eerdun Wurile improves stroke recovery through regulation of gene expression in rat brain about?
## Ethnopharmacological relevance: Eerdun wurile (ew) is one of the key mongolian medicines for treatment of neurological and cardiological disorders. ew is ranked most regularly used mongolian medicine in clinic. components of ew which mainly originate from natural products are well defined and are unique to mongolian medicine. ## Aim of the study: Although the recipe of ew contains known neuroactive chemicals originated from plants, its mechanism of action has never been elucidated at molecular level. the objective of the present study is to explore the mechanism of neuroregenerative activity of ew by focusing on the regulation of gene expression in the brain of rat model of stroke. ## Materials and methods: Rat middle cerebral artery occlusion (mcao) models were treated with ew for 15 days. then, total rnas from the cerebral cortex of rat mcao models treated with either ew or control (saline) were extracted and analyzed by transcriptome sequencing. differentially expressed genes were analyzed for their functions during the recovery of ischemic stroke. the expression level of significantly differentially expressed genes such as growth factors, microglia markers and secretive enzy
Who reads Traditional Mongolian medicine Eerdun Wurile improves stroke recovery through regulation of gene expression in rat brain?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- Gaowa, Saren; Bao, Narisi; Da, Man; Qiburi, Qiburi; Ganbold, Tsogzolmaa; Chen, Lu; Altangerel, Altanzul; Temuqile, Temuqile; Baigude, Huricha
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0378-8741)
- Published
- 2018
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)