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What is Lipid-Associated Macrophage Gene Profiles about?

This study identifies conserved and tissue-restricted transcriptional profiles for lipid-associated macrophages (LAMs) using single-cell RNA sequencing data from various tissues and inflammatory conditions. LAMs play critical roles in lipid metabolism and are implicated in diseases such as atherosclerosis and obesity, with shared markers like Trem2 and Lpl being conserved across species. The findings provide a comprehensive transcriptional landscape of LAMs, which could inform therapeutic strategies targeti

Author

ghunawatraj4

Language

EN