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Comparing Fertilization Rates from Intracytoplasmic Sperm Injection to Conventional in Vitro Fertilization Among Women of Advanced Age with Non−male Factor Infertility: a Meta-analysis by Saswati Sunderam; Sheree L. Boulet; Jennifer F. Kawwass; Dmitry M. Kissin is a Medicine article available to read on EtoBox.

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## Objective: To evaluate the effectiveness of intracytoplasmic sperm injection (icsi) in improving fertilization rates compared to conventional in vitro fertilization rates (ivf) among women aged ≥38 years with a non-male factor diagnosis. ## Design: Systematic review and meta-analysis. ## Setting: Not applicable. ## Patient(s): Women aged ≥38 years with a non-male factor diagnosis receiving ivf or icsi. ## Intervention(s): A systematic review of databases including pubmed and embase was performed. study protocol was registered at the international prospective register of systematic reviews. studies were selected if they compared fertilization rates from icsi with those from conventional ivf among women aged ≥38 years with a non-male factor infertility diagnosis. a random effects model was used. meta-analysis of observational studies in epidemiology guidelines were applied. ## Main outcome measure(s): Fertilization rate. ## Results: Seven studies including 8796 retrieved oocytes (icsi: 4,369; ivf: 4,427) with mean female age ≥38 years met the inclusion criteria. there was no significant difference in fertilization rates between icsi and conventional ivf (relative risk [rr] 0.99, 9

Who reads Comparing Fertilization Rates from Intracytoplasmic Sperm Injection to Conventional in Vitro Fertilization Among Women of Advanced Age with Non−male Factor Infertility: a Meta-analysis?

Author

Saswati Sunderam; Sheree L. Boulet; Jennifer F. Kawwass; Dmitry M. Kissin

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1556-5653)

Published

2020

Language

EN

Field

Medicine (Health Sciences)