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Cancer Cytopathology - 2025 - Wang - DICER1 Mutations in Bethesda Category II III and IV Thyroid Nodules A Mutually by lhmc40lab is a document available to read on EtoBox.
This study investigates DICER1 mutations in thyroid nodules classified as Bethesda II, III, and IV, finding a prevalence of 5.8% among 899 patients. DICER1 mutations were mutually exclusive with BRAFV600E mutations, indicating that DICER1-mutant nodules are unlikely to be BRAF-mutant carcinomas. The research highlights the need for further exploration of the molecular characteristics of DICER1-mutant fine-needle aspiration specimens for improved cytological diagnosis.
- Author
- lhmc40lab
- Language
- EN