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What is Understanding Endogenous Opioid Systems about?
The endogenous opioid system involves opioid peptides like endorphins, enkephalins, and dynorphins that bind to three primary opioid receptor types - μ, κ, and δ - which are involved in modulating pain transmission. Opioid analgesics produce their analgesic effects by mimicking and amplifying the actions of these endogenous opioid peptides, primarily through inhibiting nociceptive transmission in the central nervous system by decreasing neurotransmitter release presynaptically or hyperpolarizing postsynapti
- Author
- Likoh Timothy
- Language
- EN