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Can I read Fracture, Nonunion and Postoperative Infection Risk in the Smoking Orthopaedic Patient: a Systematic Review and Meta-analysis on EtoBox?
Fracture, Nonunion and Postoperative Infection Risk in the Smoking Orthopaedic Patient: a Systematic Review and Meta-analysis by Maria Anna Smolle; Lukas Leitner; Nikolaus Böhler; Franz-Josef Seibert; Mathias Glehr; Andreas Leithner is a Medicine article available to read on EtoBox.
What is Fracture, Nonunion and Postoperative Infection Risk in the Smoking Orthopaedic Patient: a Systematic Review and Meta-analysis about?
This systematic review and meta-analysis aimed to analyse negative effects of smoking in orthopaedic and trauma patients. A PubMed search was carried out for studies published until July 2020 regarding effects of smoking on fracture risk, nonunion, infection after orthopaedic surgery, and persisting nonunion after scaphoid nonunion surgery. Random effects models calculated for outcome parameters, and relative risks (RR) with 95% confidence intervals are provided. No adjustments for covariates were made. Heterogeneity was assessed with Higgins’ I2, publication bias with Harbord’s p (Hp), sensitivity analysis performed on funnel plots and quality of studies was analysed using the Newcastle-Ottawa Scale. Of 3362 retrieved entries, 69 were included in the final analysis. Unadjusted RR for smokers to develop vertebral (six studies, seven entries; RR: 1.61; p = 0.008; I2 = 89.4%), hip (11 studies, 15 entries; RR: 1.28; p = 0.007; I2 = 84.1%), and other fractures (eight studies, 10 entries; RR: 1.75; p = 0.019; I2 = 89.3%) was significantly higher. Postoperative infection risk was generally higher for smokers (21 studies; RR: 2.20; p < 0.001; I2 = 58.9%), and remained upon subgroup analys
Who reads Fracture, Nonunion and Postoperative Infection Risk in the Smoking Orthopaedic Patient: a Systematic Review and Meta-analysis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Maria Anna Smolle; Lukas Leitner; Nikolaus Böhler; Franz-Josef Seibert; Mathias Glehr; Andreas Leithner
- Publisher
- Bioscientifica
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)