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Herpes Zoster in Patients with Sciatica by Ke, Der-Shin; Hsu, Chao-Yu; Lin, Cheng-Li; Hsu, Chung-Y.; Kao, Chia-Hung is a Medicine article available to read on EtoBox.

What is Herpes Zoster in Patients with Sciatica about?

## Abstract ## Background Several diseases are associated with herpes zoster (HZ). However, whether sciatica is a stressor leading to HZ development remains unclear. Here, we evaluated the occurrence of HZ in patients with sciatica. ## Methods The sciatica cohort consisted of patients first diagnosed as having sciatica between 2000 and 2012. All patients with sciatica were randomly age, sex and index year matched with control individuals without sciatica. The primary outcome was diagnosis of HZ. All individuals were followed until HZ diagnosis, withdrawal from the insurance, death, or December 31, 2013, whichever occurred first. HZ risk in the two cohorts was further analyzed with age, sex and comorbidity stratification. ## Results In total, 49,023 patients with sciatica and 49,023 matched controls were included. Female patients were more likely to have HZ development than were male patients [adjusted hazard ratio (HR) = 1.07, 95% confidence interval (CI) = 1.02–1.12]. After adjustments for all the covariates, HZ risk was significantly higher in the sciatica cohort than in the control cohort (adjusted HR = 1.19; 95% CI = 1.12–1.25). ## Conclusion Sciatica increased HZ risk. Thus, H

Who reads Herpes Zoster in Patients with Sciatica?

Author

Ke, Der-Shin; Hsu, Chao-Yu; Lin, Cheng-Li; Hsu, Chung-Y.; Kao, Chia-Hung

Publisher

BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2000-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-2474)

Published

2020

Language

EN

Field

Medicine (Health Sciences)