Can I read Host-Targeted Antiviral Strategies on EtoBox?
Host-Targeted Antiviral Strategies by Abdul-Ganiyu Mannir is a document available to read on EtoBox.
What is Host-Targeted Antiviral Strategies about?
The document discusses how certain kinase inhibitors that target host cell pathways can exert broad-spectrum antiviral effects against multiple viruses. It shows that the host adaptor proteins AP1 and AP2 traffic with hepatitis C virus and are exploited by other viruses as well. Treatment with anticancer drugs sunitinib and erlotinib, which inhibit the host kinases AAK1 and GAK, blocked intracellular trafficking of hepatitis C virus and other unrelated RNA viruses. These drugs also protected mice against de
- Author
- Abdul-Ganiyu Mannir
- Language
- EN