About this document
Overview of Myelofibrosis by Destrini Anjani Landa is a document available to read on EtoBox.
Myelofibrosis is a myeloproliferative disorder characterized by bone marrow fibrosis, splenomegaly, and extramedullary hematopoiesis. It results from clonal proliferation of hematopoietic stem cells. Patients typically present with anemia, thrombocytopenia, and an enlarged spleen. The diagnosis is made through blood smears, bone marrow biopsy showing hypercellularity and reticulin fibrosis. Treatment focuses on managing symptoms like anemia, thrombocytopenia, and splenomegaly. The median survival is 5 years
- Author
- Destrini Anjani Landa
- Language
- EN