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The Reorganization of Motor Units in Motor Neuron Disease by Prof Barbara Emeryk-Szajewska; Jerzy Kopeć; Anna Karwanska is a Medicine article available to read on EtoBox.

What is The Reorganization of Motor Units in Motor Neuron Disease about?

We studied 78 patients with motor neuron disease (MND) using concentric needle electromyography. Analysis on weak and maximal effort was performed using our own, fully automated, computer method, EMG-LAB. In addition to the conventional parameters of single motor unit action potentials (MUAPs) and interference pattern, new criteria were applied: the range of the acting motor units and the functional recruitment order. A total of 375 muscles of MND patients and 120 control muscles were investigated. The electromyographic data were analyzed separately in five groups of muscles, classified A, B, C, D, and E according to their clinical condition. Those results allowed us to discern six neurophysiological stages (N 0,1,2,3,4,5 ) from the early to the most advanced phase. It has been confirmed that reinnervation in MND is adequate to compensate for the loss of over 50% of motor neurons but it is only a transitory phase in the morbid course. At stages N 0-5 , the electrophysiological data reflect structural and functional integrity of the functioning motor units. Evaluation of not only single MUAPs but also of the full range of acting motor units and their recruitment order allowed a deep

Who reads The Reorganization of Motor Units in Motor Neuron Disease?

Author

Prof Barbara Emeryk-Szajewska; Jerzy Kopeć; Anna Karwanska

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0148-639X)

Published

1997

Language

EN

Field

Medicine (Health Sciences)