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Clinical Feasibility of a New Antireflux Ablation Therapy on Gastroesophageal Reflux Disease (with Video) by Oscar Víctor Hernández Mondragón; Raúl Antonio Zamarripa Mottú; Luís Fernando García Contreras; Raul Alberto Gutiérrez Aguilar; Omar Michel Solórzano Pineda; Gerardo Blanco Velasco; Enrique Murcio Perez is a Medicine article available to read on EtoBox.

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## Backgrounds and aims: New mucosal resective and ablative endoscopic procedures based on gastric cardiac remodeling to prevent reflux have appeared. we aimed to evaluate the feasibility of a new ablative technique named antireflux ablation therapy (arat) for control of gerd in patients without hiatal hernia. ## Methods: Patients with proton pump inhibitor (ppi)-refractory gerd without hiatal hernia underwent arat between january 2016 and october 2019. gastroesophageal reflux disease-health-related quality of life (gerd-hrql), upper endoscopy, 24-hour ph monitoring, and ppi use were documented at 3, 6, 12, 24, and 36 months after arat. ## Results: One hundred eight patients were included (61 men [56.5%]; median age, 36.5 years; range, 18-78 years). arat was performed on all patients. at the 36-month evaluation, 84 patients had completed the protocol. median arat time was 35.5 minutes (range, 22-51 minutes), and median circumference ablation was 300° (range, 270°-320°). no major adverse events occurred, and 14 of 108 patients (12.9%) presented with stenosis that was responsive to balloon dilation (<5 sessions). at the 3-month evaluation, the acid exposure time (aet), demeester scor

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Author

Oscar Víctor Hernández Mondragón; Raúl Antonio Zamarripa Mottú; Luís Fernando García Contreras; Raul Alberto Gutiérrez Aguilar; Omar Michel Solórzano Pineda; Gerardo Blanco Velasco; Enrique Murcio Perez

Publisher

Elsevier BV

Published

2020

Language

EN

Field

Medicine (Health Sciences)