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Do prenatal factors shape the risk for dementia?: A systematic review of the epidemiological evidence for the prenatal origins of dementia by Aline Marileen Wiegersma; Amber Boots; Miranda W. Langendam; Jacqueline Limpens; Susan D. Shenkin; Aniko Korosi; Tessa J. Roseboom; Susanne R. de Rooij is a Psychology article available to read on EtoBox.
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Abstract Purpose Prenatal factors such as maternal stress, infection and nutrition affect fetal brain development and may also influence later risk for dementia. The purpose of this systematic review was to provide an overview of all studies which investigated the association between prenatal factors and later risk for dementia. Methods We systematically searched MEDLINE and Embase for original human studies reporting on associations between prenatal factors and dementia from inception to 23 November 2022. Prenatal factors could be any factor assessed during pregnancy, at birth or postnatally, provided they were indicative of a prenatal exposure. Risk of bias was assessed using the Newcastle Ottawa Scale. We followed PRISMA guidelines for reporting. Results A total of 68 studies met eligibility criteria (including millions of individuals), assessing maternal age (N = 30), paternal age (N = 22), birth order (N = 15), season of birth (N = 16), place of birth (N = 13), prenatal influenza pandemic (N = 1) or Chinese famine exposure (N = 1), birth characteristics (N = 3) and prenatal hormone exposure (N = 4). We observed consistent results for birth in a generally less optimal environme
Who reads Do prenatal factors shape the risk for dementia?: A systematic review of the epidemiological evidence for the prenatal origins of dementia?
It is typically read by researchers, students, and practitioners in Psychology.
- Author
- Aline Marileen Wiegersma; Amber Boots; Miranda W. Langendam; Jacqueline Limpens; Susan D. Shenkin; Aniko Korosi; Tessa J. Roseboom; Susanne R. de Rooij
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Psychology (Social Sciences)