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Can I read Deep Brain Stimulation for Major Depression on EtoBox?
Deep Brain Stimulation for Major Depression by T.E. Schlaepfer; B.H. Bewernick is a Medicine article available to read on EtoBox.
What is Deep Brain Stimulation for Major Depression about?
A third of patients suffering from major depression cannot be helped by conventional treatment methods. These patients face reduced quality of life, high risk of suicide, and little hope of recovery. Deep brain stimulation (DBS) is under scientific evaluation as a new treatment option for these treatment-resistant patients. First clinical studies with small samples have been stimulated at the subgenual cingulate gyrus (Cg25/24), the anterior limb of the capsula interna (ALIC), and the nucleus accumbens (NAcc). Long-term antidepressant effects, augmentation of social functioning, and normalization of brain metabolism have been shown in about 50% of patients. Cognitive safety regarding attention, learning, and memory has been reported. Adverse events were wound infection, suicide, and hypomania, amongst others. Larger studies are under way to confirm these preliminary encouraging results. New hypothesis-guided targets (e.g., medial forebrain bundle, habenula) are about to be assessed in clinical trials. The application of DBS for other psychiatric diseases (e.g., bipolar disorder, alcohol dependency, opioid addiction, schizophrenia) is debated and single case studies are under way. S
Who reads Deep Brain Stimulation for Major Depression?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- T.E. Schlaepfer; B.H. Bewernick
- Published
- 2013
- Language
- EN
- Field
- Medicine (Health Sciences)