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1. Quinolones are a class of synthetic antimicrobials that are primarily active against gram-negative bacteria. Newer fluoroquinolones also inhibit gram-positive bacteria. 2. First-generation fluoroquinolones like norfloxacin and ofloxacin gained broader spectra of activity compared to early quinolones. Newer second-generation fluoroquinolones have even greater activity against both gram-positive and gram-negative bacteria. 3. Fluoroquinolones work by inhibiting the bacterial enzymes DNA gyrase and topoi
- Author
- Jithin Gangadharan
- Language
- EN