Can I read Antineoplastics/von-willebrand-factor: Constipation and lack of efficacy: 2 case reports on EtoBox?

Antineoplastics/von-willebrand-factor: Constipation and lack of efficacy: 2 case reports is a Medicine article available to read on EtoBox.

What is Antineoplastics/von-willebrand-factor: Constipation and lack of efficacy: 2 case reports about?

## S Antineoplastics/von-willebrand-factor Constipation and lack of efficacy: 2 case reports In a series of three cases, 2 women aged 64 years were described, of whom one woman developed constipation during treatment with bortezomib, dexamethasone and rituximab, and another woman exhibited lack of efficacy during treatment with von Willebrand factor for Acquired von Willebrand syndrome (AVWS) [routes, dosages and outcomes not stated]. Case 2 from the article: A 64-year-old woman, who was diagnosed with Waldenstrom's Macroglobulinaemia and AVWS, presented without bleeding diathesis. She was initiated on bortezomib, dexamethasone and rituximab. After the fourth cycle, she developed a large rectus sheath haematoma, which was considered as secondary to the chemotherapy‐induced constipation. She was hospitalised and received treatment with von Willebrand factor [FVIII/VWF] concentrates. Therapy with bortezomib was changed to cyclophosphamide. She achieved a partial response, and no more haemorrhagic events were noted during the follow‐up examinations. Case 3 from the article: A 64-year-old woman, who was diagnosed with monoclonal gammopathy of undetermined significance IgG‐Kappa and AVW

Who reads Antineoplastics/von-willebrand-factor: Constipation and lack of efficacy: 2 case reports?

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)