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Wound-healing activity of glycoproteins from white jade snail (Achatina fulica) on experimentally burned mice by Yiming Song; Yinxin Cui; Limin Hao; Jiaqing Zhu; Juanjuan Yi; Qiaozhen Kang; Jinyong Huang; Jike Lu is a Materials Science article available to read on EtoBox.
What is Wound-healing activity of glycoproteins from white jade snail (Achatina fulica) on experimentally burned mice about?
Burns are a global public health problem and the treatment of burn wounds is a major medical and economic issue. White jade snails (Achatina fulica) are now widely distributed in Asia, and they have been used to treat burns in folk medicine of China. In this study, the glycoproteins from white jade snails were investigated and their effect on burn healing was evaluated by a mouse burn model. The results showed that the snail mucus was mainly composed of proteins and polysaccharides, and it had good adhesion. The main component of snail mucus was glycoprotein from the results of DEAE Sepharose FF ion exchange chromatography. The 2,2-Diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging effect of 1 mg/mL snail mucus reached 13.77%. The wound healing rate of the snail mucus group was higher than that of the control group (p < 0.0001). Histopathological results showed that mice in the snail mucus group had a faster healing than that of the control group. The biochemical analysis was in agreement with the histopathological findings. These results suggested that glycoproteins from snail mucus showed effective wound healing activities in the skin of experimentally burned mice.
Who reads Wound-healing activity of glycoproteins from white jade snail (Achatina fulica) on experimentally burned mice?
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Yiming Song; Yinxin Cui; Limin Hao; Jiaqing Zhu; Juanjuan Yi; Qiaozhen Kang; Jinyong Huang; Jike Lu
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Materials Science (Physical Sciences)