Can I read Osteoarthritic Joint Pain (Novartis Foundation Symposia) on EtoBox?

Osteoarthritic Joint Pain (Novartis Foundation Symposia) by Derek Chadwick; Jamie Goode; Novartis Foundation is a nonfiction available to read on EtoBox.

What is Osteoarthritic Joint Pain (Novartis Foundation Symposia) about?

Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of every 100 people and significantly reduces the quality of life in affected individuals. The major symptoms are chronic pain, swelling and stiffness; severe, chronic joint pain is often the central factor that causes patients to seek medical attention. Within the affected joint, there is focal degradation and remodelling of articular cartilage, new bone formation (osteophytes) and mild synovitis. Several mechanisms are thought to contribute to osteoarthritic joint pain. These include mild synovial inflammation, bone oedema, ligament stretching, osteophyte formation and cartilage-derived mediators. Changes in joint biomechanics and muscle strength also influence the severity and duration of joint pain in osteoarthritis. Within the nervous system, the relative contributions of peripheral afferent nociceptive fibres and central mechanisms remain to be defined, and there is limited information on the phenotype of sensory neurons in the OA joint. Importantly, there is no relation between clinical severity, as measured by radiographic changes,

Who reads Osteoarthritic Joint Pain (Novartis Foundation Symposia)?

Author

Derek Chadwick; Jamie Goode; Novartis Foundation

Publisher

Wiley & Sons, Incorporated, John

Published

2004

Language

EN

ISBN

9780470867587

Category

nonfiction

Subjects

Medical, Stem