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Antigen processing and presentation involves two pathways: endogenous and exogenous. The endogenous pathway involves degradation of intracellular proteins by the proteasome, transport of peptides to the ER by TAP, and loading of peptides onto MHC I for presentation at the cell surface. The exogenous pathway involves uptake of extracellular proteins by APCs, degradation into peptides in the endosome, and loading of peptides onto MHC II for presentation at the cell surface. APCs such as dendritic cells, macro

Author

Gana Khaled

Language

EN