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FDG PET for the study of primary hepatic malignancies in children by Rajen J. Mody; Judith A. Pohlen; Sachit Malde; Peter J. Strouse; Barry L. Shulkin is a Medicine article available to read on EtoBox.

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## Abstract ## Purpose This manuscript describes the use of FDG PET in a series of 7 children (11 scans) with primary hepatic malignancies (5 patients with hepatoblastoma, 2 patients with hepatic embryonal rhabdomyosarcoma), together with other imaging (CT and MRI), serum tumor markers, and tumor pathology. ## Materials and Methods Seven children with pathologically proven hepatic malignancies underwent 11 FDG PET scans for staging (1 patient) or restaging (6 patients). Tumor uptake of FDG was assessed qualitatively and compared with biochemical and radiological findings. ## Results Abnormal uptake was demonstrated in 6 of 7 patients (10 of 11 scans). Three patients subsequently underwent partial hepatic resection, and one underwent brain biopsy, confirming in each that the abnormal uptake of FDG indicated viable tumor. In one patient, intense uptake was due to necrotizing granulomas. In one patient, images were suboptimal due to noncompliance with fasting. ## Conclusion Primary hepatic tumors of childhood usually demonstrate increased glycolytic activity, which allows them to be imaged using PET and the tracer 18F‐FDG. The technique is probably most useful for assessing response t

Who reads FDG PET for the study of primary hepatic malignancies in children?

Author

Rajen J. Mody; Judith A. Pohlen; Sachit Malde; Peter J. Strouse; Barry L. Shulkin

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1545-5009)

Published

2005

Language

EN

Field

Medicine (Health Sciences)