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The Effect of em FTO em Variation On Increased by Mari is a document available to read on EtoBox.
This study investigates the relationship between the FTO gene variant rs8044769 and the risk of osteoarthritis (OA) in relation to body mass index (BMI). It finds that the association between the FTO variant and OA risk is mediated by BMI, with no direct effect of the gene variant on OA when BMI is accounted for. The results highlight the importance of overweight as a causal factor for OA, emphasizing the role of obesity in OA pathogenesis.
- Author
- Mari
- Language
- EN