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Synthesis, characterization, biological studies, molecular docking and theoretical calculation of some transition metal com ... 1 Introduction 1 2 Experimental 4 2.1 Materials and measurements 4 2.2 General synthesis of azo dye ligand and metal complexes 5 2.2.1 Synthesis of 2-[2′-(6-methoxy benzothiazolyl)azo]-3-methyl-4-nitrophenol (LH) (6-MBTAMN) 5 2.2.2 General synthesis of the metal complexes 6 2.2.2.1 [Ag(L)(H2O)] 6 2.2.2.2 [Pt(L)2]Cl2·H2O 6 2.2.2.3 [Au(L)Cl]Cl·H2O 6 2.3 Antimicrobial study (in vitro) 7 2.4 Molecular docking 7 2.5 Antiradical assay 8 2.6 Cell culture 9 2.7 Cytotoxic Studies-MTT assay 9 2.8 Statistical analysis 10 3 Results and discussion 10 3.1 Electronic spectra 10 3.2 X-ray diffraction analysis (XRD) 12 3.3 Computational study 12 3.4 Antimicrobial activity 13 3.5 Docking study 13 3.6 In-vitro antiradical activity 13 3.7 MTT cytotoxicity analysis 13 4 Conclusion 14 CRediT authorship contribution statement 14 Declaration of Competing Interest 14 Data availability 14 Acknowledgements 14 Funding 14 Data availability 14 Ethics approval 14 Consent for publication 14 Appendix A Supplementary data 14 References 14
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Common subject areas: history, science, philosophy, social sciences.
- Language
- EN
- Category
- nonfiction
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