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Strategies for Assessing the Impact of Loss to Follow-up on Estimates of Neurodevelopmental Impairment in a Very Preterm Cohort at 2 Years of Age by Piedvache, Aurélie (author);van Buuren, Stef (author);Barros, Henrique (author);Ribeiro, Ana Isabel (author);Draper, Elizabeth (author);Zeitlin, Jennifer (author);, the EPICE Research group (author);Martens, E. (author);Martens, G. (author);Van Reempts, P. (author);Boerch, K. (author);Hasselager, A. (author);Huusom, L. D. (author);Pryds, O. (author);Weber, T. (author);Toome, L. (author);Varendi, H. (author);France, Ile-de (author);Ancel, P. Y. (author);Blondel, B. (author);Burguet, A. (author);Jarreau, P. H. (author);Truffert, P. (author);Maier, R. F. (author);Misselwitz, B. (author);Schmidt, S. (author);Gortner, L. (author);Baronciani, D. (author);Gargano, G. (author);Agostino, R. (author);DiLallo, D. (author);Franco, F. (author);Carnielli, V. (author);Koopman-Esseboom, C. (author);van Heijst, A. (author);Nijman, J. (author);Gadzinowski, J. (author);Mazela, J. (author);Graça, L. M. (author);Machado, M. C. (author);Rodrigues, Carina (author);Rodrigues, T. (author);Bonamy, A. K. (author);Norman, M. (author);Boyle, E. Wilson E (author);Draper, E. S. (author);Manktelow, B. N. (author);Fenton, A. C. (author);Milligan, D. W. A. (author);Zeitlin, J. (author);Bonet, M. (author);Piedvache, A. (author) is a Mathematics article available to read on EtoBox.

What is Strategies for Assessing the Impact of Loss to Follow-up on Estimates of Neurodevelopmental Impairment in a Very Preterm Cohort at 2 Years of Age about?

## Background Loss to follow-up is a major challenge for very preterm (VPT) cohorts; attrition is associated with social disadvantage and parents with impaired children may participate less in research. We investigated the impact of loss to follow-up on the estimated prevalence of neurodevelopmental impairment in a VPT cohort using different methodological approaches. ## Methods This study includes births < 32 weeks of gestational age (GA) from 4 regions in the UK and Portugal participating in a European birth cohort (__N__ = 1737 survivors). Data on maternal characteristics, pregnancy complications, neonatal outcomes and neighborhood deprivation were collected at baseline. Neurodevelopment was assessed at 2 years of corrected age (CA) using standardized parent-report measures. We applied (1) multiple imputation (MI) and (2) inverse probability weighting (IPW) to estimate the impact of non-response on the prevalence of moderate to severe neurodevelopmental impairment and assessed violations of the missing at random (MAR) assumption using the delta method. ## Results 54.2% of children were followed-up. Follow-up was less likely when mothers were younger, multiparous, foreign-born, d

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Author
Piedvache, Aurélie (author);van Buuren, Stef (author);Barros, Henrique (author);Ribeiro, Ana Isabel (author);Draper, Elizabeth (author);Zeitlin, Jennifer (author);, the EPICE Research group (author);Martens, E. (author);Martens, G. (author);Van Reempts, P. (author);Boerch, K. (author);Hasselager, A. (author);Huusom, L. D. (author);Pryds, O. (author);Weber, T. (author);Toome, L. (author);Varendi, H. (author);France, Ile-de (author);Ancel, P. Y. (author);Blondel, B. (author);Burguet, A. (author);Jarreau, P. H. (author);Truffert, P. (author);Maier, R. F. (author);Misselwitz, B. (author);Schmidt, S. (author);Gortner, L. (author);Baronciani, D. (author);Gargano, G. (author);Agostino, R. (author);DiLallo, D. (author);Franco, F. (author);Carnielli, V. (author);Koopman-Esseboom, C. (author);van Heijst, A. (author);Nijman, J. (author);Gadzinowski, J. (author);Mazela, J. (author);Graça, L. M. (author);Machado, M. C. (author);Rodrigues, Carina (author);Rodrigues, T. (author);Bonamy, A. K. (author);Norman, M. (author);Boyle, E. Wilson E (author);Draper, E. S. (author);Manktelow, B. N. (author);Fenton, A. C. (author);Milligan, D. W. A. (author);Zeitlin, J. (author);Bonet, M. (author);Piedvache, A. (author)
Publisher
Springer Science and Business Media LLC
Published
2021
Language
EN
Field
Mathematics (Physical Sciences)

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