Opening book details…
Can I read Mapping of serotonin transporters by positron emission tomography with [^11^c]DASB in conscious common marmosets: Comparison with rhesus monkeys on EtoBox?
Mapping of serotonin transporters by positron emission tomography with [^11^c]DASB in conscious common marmosets: Comparison with rhesus monkeys by Chihiro Yokoyama; Hajime Yamanaka; Kayo Onoe; Akihiro Kawasaki; Hiroko Nagata; Keiko Shirakami; Hisashi Doi; Hirotaka Onoe is a Neuroscience article available to read on EtoBox.
What is Mapping of serotonin transporters by positron emission tomography with [^11^c]DASB in conscious common marmosets: Comparison with rhesus monkeys about?
## Abstract The common marmoset (__Callithrix jacchus__) is unique among the primates in its small body size, reproductive efficacy, and characteristic social behavior, making it useful as an animal model in neuroscientific research. To assess the brain serotonergic systems, we investigated the binding of [^11^C]‐3‐amino‐4‐(2‐dimetylaminomethyl‐phenylsulfanyl)‐benzonitrile ([^11^C]DASB) to brain serotonin transporter (SERT) in conscious common marmosets using positron emission tomography (PET), and compared with findings for rhesus monkeys. Both species showed globally similar distribution patterns of [^11^C]DASB uptake in the brain, with highest activity in the midline of the brain and lowest in the cerebellum, and higher activity in some subcortical regions than in surrounding cortex, while the common marmoset brain showed almost equal or rather higher binding potential (BP) values (BP~ND~) in cortical regions and hippocampus, and lower BP~ND~ than the rhesus monkey brain in some subcortical regions. Test‐retest reproducibility of BP~ND~ at an interval of several months was high, indicating reliable and stable measurements of serotonin transporters in both species. These results
Who reads Mapping of serotonin transporters by positron emission tomography with [^11^c]DASB in conscious common marmosets: Comparison with rhesus monkeys?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Chihiro Yokoyama; Hajime Yamanaka; Kayo Onoe; Akihiro Kawasaki; Hiroko Nagata; Keiko Shirakami; Hisashi Doi; Hirotaka Onoe
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0887-4476)
- Published
- 2010
- Language
- EN
- Field
- Neuroscience (Life Sciences)