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What is Understanding CFTR Protein Function about?

Cystic fibrosis is caused by mutations in the CFTR gene that result in the CFTR protein being dysfunctional or not produced. The CFTR protein functions as an ion channel that transports chloride ions in and out of cells, maintaining proper hydration of the mucus on lung surfaces. When the CFTR protein is broken, thick mucus builds up in the lungs and leads to frequent infections. Understanding the structure and function of the CFTR protein is important for developing new treatments for cystic fibrosis.

Author

Sunayana Raju

Language

EN