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The study demonstrates that systemic delivery of synthetic microRNA-16 (miR-16) significantly inhibits the growth of metastatic prostate tumors by downregulating multiple cell-cycle genes. In vitro and in vivo experiments indicate that miR-16 reduces cell proliferation and promotes apoptosis in various prostate cancer cell lines, with effective delivery achieved via atelocollagen in a mouse model. These findings suggest the potential of miR-16 as a therapeutic agent for advanced prostate cancer treatment.

Author

aristogratgamersanddavidchristmas

Language

EN