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Weak and Uneven Associations of Home, Neighborhood, and School Environments with Stress Hormone Output Across Multiple Timescales by Margherita Malanchini; Laura E. Engelhardt; Laurel A. Raffington; Aditi Sabhlok; Andrew D. Grotzinger; Daniel A. Briley; James W. Madole; Samantha M. Freis; Megan W. Patterson; K. Paige Harden; Elliot M. Tucker-Drob is a Neuroscience article available to read on EtoBox.

What is Weak and Uneven Associations of Home, Neighborhood, and School Environments with Stress Hormone Output Across Multiple Timescales about?

The progression of lifelong trajectories of socioeconomic inequalities in health and mortality begins in childhood. Dysregulation in cortisol, a stress hormone that is the primary output of the hypothalamus-pituitary-adrenal (HPA) axis, has been hypothesized to be a mechanism for how early environmental adversity compromises health. However, despite the popularity of cortisol as a biomarker for stress and adversity, little is known about whether cortisol output differs in children being raised in socioeconomically disadvantaged environments. Here, we show that there are few differences between advantaged and disadvantaged children in their cortisol output. In 8-14-year-old children from the population-based Texas Twin Project, we measured cortisol output at three different timescales: (a) diurnal fluctuation in salivary cortisol (n = 400), (b) salivary cortisol reactivity and recovery after exposure to the Trier Social Stress Test (n = 444), and (c) cortisol concentration in hair (n = 1210). These measures converged on two moderately correlated, yet distinguishable, dimensions of HPA function. We tested differences in cortisol output across nine aspects of social disadvantage at th

Who reads Weak and Uneven Associations of Home, Neighborhood, and School Environments with Stress Hormone Output Across Multiple Timescales?

Author

Margherita Malanchini; Laura E. Engelhardt; Laurel A. Raffington; Aditi Sabhlok; Andrew D. Grotzinger; Daniel A. Briley; James W. Madole; Samantha M. Freis; Megan W. Patterson; K. Paige Harden; Elliot M. Tucker-Drob

Publisher

Nature Publishing Group; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1359-4184)

Published

2020

Language

EN

Field

Neuroscience (Life Sciences)