Can I read Modeling chromatographic dispersion: A comparison of popular equations on EtoBox?

Modeling chromatographic dispersion: A comparison of popular equations by Karyn M. Usher; Carolyn R. Simmons; John G. Dorsey is a Chemistry article available to read on EtoBox.

What is Modeling chromatographic dispersion: A comparison of popular equations about?

An analyte that is introduced onto a column as a finite band broadens as it moves along the column. This band-broadening is generally attributed to three independent processes, including flow path inequalities, molecular diffusion, and resistance to mass transfer. Many equations have been derived in attempts to mathematically model the process. Some of the more popular of these include the equations of van Deemter, Giddings, Horvath and Lin, and Knox. Although the basis of each equation is theoretically different, the differences among them are minor, and most of the equations can be used to adequately fit plate height data. Chromatographers often collect efficiency data to monitor the performance of their columns, and then use one of the above equations to fit the data. The choice of which equation to use can be daunting, since the theories are conflicting. Using an extensive collection of data, we have compared these equations on the basis of the resulting fit. This study was performed using analytes covering a wide range of retention values and mobile phases of differing strengths. The Foley-Dorsey equation was used to calculate the number of theoretical plates for the efficienc

Who reads Modeling chromatographic dispersion: A comparison of popular equations?

Author

Karyn M. Usher; Carolyn R. Simmons; John G. Dorsey

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1873-3778)

Published

2008

Language

EN

Field

Chemistry (Physical Sciences)