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What is Enhancing Itraconazole Solubility via Cocrystallization about?

This study investigates the use of pharmaceutical cocrystallization to enhance the solubility and bioavailability of itraconazole, a poorly soluble antifungal drug. The optimized cocrystal formulation demonstrated significant improvements in solubility and dissolution rate compared to pure itraconazole, with pharmacokinetic studies showing a notable increase in drug absorption in rats. The findings suggest that cocrystal technology could effectively address formulation challenges and improve therapeutic out

Author

Mehmet Can Yılmaz

Language

EN