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Susceptibility of Clinical Isolates of Campylobacter Pylori to 24 Antimicrobial and Anti-ulcer Agents by Y. Glupczynski; M. Delmee; C. Bruck; M. Labbe; V. Avesani; A. Burette is a Medicine article available to read on EtoBox.
What is Susceptibility of Clinical Isolates of Campylobacter Pylori to 24 Antimicrobial and Anti-ulcer Agents about?
Forty-nine isolates of Campylobacler pylori were tested for their susceptibility to twenty antibiotics and four anti-ulcer a~ents by an agar dilution technique. Penicillin and amoxycillin were the most active drugs ('MICg0, 0.06 Ixg/ml); erythromycin, cefazolin, minocycline, ciprofloxacin, ofloxacin and gentamicin were sligthtly less active (MICg0, G 1 l~g/ml). Moderate activity was found for doxycyclin, rifampin, nitrofurantoin, norfloxacin, pefloxacin, enoxacin, paromomycin, metronidazole and tinidazole. All strains were resistant to trimethoprim (MIC > 512 I~g/ml). N.alidixic ,acid (MICg0, > 256 lxg/ml) and colistin (MICgo, > 64 Izg/ml) had little to fro .activity. Of four anti-ulcer drugs, only bismuth subcitrate showed activity (MICo0, 64 Ixg/ml). Strains resistant to all 4-quinolones were found in patients who had previously received ofloxaein as part of a clinical trial aimed at eradication of C. pylori. These isolates remained susceptible to amoxycillin, tetracyclines and to other classes of antibiotics.
Who reads Susceptibility of Clinical Isolates of Campylobacter Pylori to 24 Antimicrobial and Anti-ulcer Agents?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Y. Glupczynski; M. Delmee; C. Bruck; M. Labbe; V. Avesani; A. Burette
- Publisher
- Springer; Springer-Verlag; Kluwer Academic Publishers; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0393-2990)
- Published
- 1988
- Language
- EN
- Field
- Medicine (Health Sciences)