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This study developed an ELISA-based system to evaluate the neutralization potency of equine plasma against Naja atra venom, providing an alternative to the labor-intensive and ethically concerning in vivo assays currently used. The ELISA demonstrated high sensitivity and specificity, particularly using the neurotoxin-derived peptide NTX1-10, which effectively discriminated between high and low potency plasma samples. This method has the potential to enhance animal welfare and efficiency in antivenom product

Author

Carlos Bello

Language

EN