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Low growth hormone levels predict poor outcome of hepatitis B virus-related acute-on-chronic liver failure by Zhongyang Xie; Lingjian Zhang; Xiaowei Xu; Lanjuan Li is a Medicine article available to read on EtoBox.

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baseline-detected, 90 baseline-PLS, 18 development, 9 development-PLS), 653 with permanently normal ALP (49.3%). 99/673 (14.7%; CI95% 12-17.3) were identified as PLS. Of them, 26/99 have been contacted and retrieved for now (characteristics in Table 1). PBC has been confirmed and Ursodeoxycholic acid started in all. PBC development rate in patients with normal baseline ALP was 3.9% (27/680; median follow-up 2.96 ± 2.41 years). DT was 2.06 ± 3.89 years. Table 1: Characteristics of retrieved patients N = 26 (%) Women 24 (92) Other autoimmune disease 12 (46) Pruritus 2 (7) Fatigue 7 (26) Elastography > 9.5 kPa 7/24 (29) Median (IQR) Age (years) 70 (60-80) Body Mass Index (kg/m 2 ) 27 (26-29.2) ALP (UI/L) 185 (135-321) GGT (UI/L) 101 (70-204) Bilirubin (mg/dL) 0.6 (0.42-0.96) Elastography (kPa) 7.1 (5.2-10) Conclusion: Up to 14.7% patients (1 out of 7) with definitive diagnostic results of PBC remain undetected, preventing their monitoring and treatment. An effort to identify and retrieve these lost-in-the-system patients is necessary. The use of hospital databases is an appropriate tool. Cirrhosis: ACLF and Critical illness FRI182 Low growth hormone levels predict poor outcome of hepa

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Author

Zhongyang Xie; Lingjian Zhang; Xiaowei Xu; Lanjuan Li

Publisher

Elsevier Science; Elsevier ; Elsevier BV; Wiley (ISSN 0168-8278)

Published

2020

Language

EN

Field

Medicine (Health Sciences)