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The Effects of Medications on Bone by Stuart B. Goodman; William Jiranek; Edward Petrow; Alan W. Yasko is a Medicine article available to read on EtoBox.

What is The Effects of Medications on Bone about?

Medications taken for the treatment of arthritis and psychotropic and epileptic disorders, as well as anticoagulants, antacids, bisphosphonates, corticosteroids, and antineoplastic drugs, can profoundly affect bone metabolism. In some scenarios (eg, osteoporosis), these effects are intended; in others (eg, rickets, osteomalacia secondary to antiepileptic drugs), potentially adverse side effects of medications on bone may occur. Nonsteroidal anti-inflammatory drugs appear to delay fracture healing and bone ingrowth, although these effects are reversible. Disease-modifying antirheumatic drugs do not appear to affect bone metabolism adversely when taken in the low dosages currently prescribed. Bisphosphonates are useful in restoring bone mass in cases of postmenopausal osteoporosis, glucocorticoid-induced osteoporosis, Paget's disease, and neoplastic conditions with bone loss and hypercalcemia. Corticosteroids and cancer chemotherapeutic agents generally affect bone adversely and increase fracture risk.

Who reads The Effects of Medications on Bone?

Author

Stuart B. Goodman; William Jiranek; Edward Petrow; Alan W. Yasko

Publisher

Ovid Technologies (Wolters Kluwer Health)

Published

2007

Language

EN

Field

Medicine (Health Sciences)