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What is MSC Secretome in Acute vs. Chronic Wound Healing about?

This study investigates the secretome of bone marrow-derived Mesenchymal Stem Cells (MSCs) from patients with acute injuries requiring amputation compared to those with chronic knee Osteoarthritis (kOA). The results indicate that MSCs from acutely ill patients secrete significantly higher levels of pro-inflammatory cytokines (IL-6, IL-8, IL-17A, MCP-1) and one anti-inflammatory cytokine (IL-10), suggesting distinct inflammatory profiles that could inform therapeutic strategies for wound healing. Understandi

Author

Athenaeum Scientific Publishers

Language

EN