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Real-time monitoring of a digestive tract marker to reduce adverse effects of moving organs at risk (OAR) in radiotherapy for thoracic and abdominal tumors by Takayuki Hashimoto; Hiroki Shirato; Mototsugu Kato; Koichi Yamazaki; Nobuaki Kurauchi; Toshiaki Morikawa; Shinichi Shimizu; Yong Chan Ahn; Yasuyuki Akine; Kazuo Miyasaka is a Medicine article available to read on EtoBox.
What is Real-time monitoring of a digestive tract marker to reduce adverse effects of moving organs at risk (OAR) in radiotherapy for thoracic and abdominal tumors about?
## Purpose: To evaluate the feasibility of real-time monitoring of a fiducial marker in/near the digestive tract and to analyze the motion of organs at risk to determine a reasonable internal margin. ## Methods and materials: We developed two methods to insert a fiducial marker into/near the digestive tract adjacent to the target volume. one method involves an intraoperative insertion technique, and the other involves endoscopic insertion into the submucosal layer of the normal digestive tract. a fluoroscopic real-time tumor-tracking radiotherapy system was used to monitor the marker. ## Results: Fourteen markers (2 in the mediastinum and 12 in the abdomen) were implanted intraoperatively in 14 patients with no apparent migration. seventeen of 20 markers (13/14 in the esophagus, 1/2 in the stomach, and 3/4 in the duodenum) in 18 patients were implanted using endoscopy without dropping. no symptomatic adverse effects related to insertion were observed. the mean/standard deviation of the range of motion of the esophagus was 3.5/1.8, 8.3/3.8, and 4.0/2.6 mm for lateral, craniocaudal and anteroposterior directions, respectively, in patients with intrafractional tumor motion less than 1
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- Author
- Takayuki Hashimoto; Hiroki Shirato; Mototsugu Kato; Koichi Yamazaki; Nobuaki Kurauchi; Toshiaki Morikawa; Shinichi Shimizu; Yong Chan Ahn; Yasuyuki Akine; Kazuo Miyasaka
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
- Published
- 2005
- Language
- EN
- Field
- Medicine (Health Sciences)