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Effect of Intensive vs Moderate Alveolar Recruitment Strategies Added to Lung-Protective Ventilation on Postoperative Pulmonary Complications: A Randomized Clinical Trial by Alcino Costa Leme; Ludhmila Abrahao Hajjar; Marcia S. Volpe; Julia Tizue Fukushima; Roberta Ribeiro De Santis Santiago; Eduardo A. Osawa; Juliano Pinheiro de Almeida; Aline Muller Gerent; Rafael Alves Franco; Maria Ignez Zanetti Feltrim; Emília Nozawa; Vera Regina de Moraes Coimbra; Rafael de Moraes Ianotti; Clarice Shiguemi Hashizume; Roberto Kalil Filho; Jose Otavio Costa Auler; Fabio Biscegli Jatene; Filomena Regina Barbosa Gomes Galas; Marcelo Britto Passos Amato is a Medicine article available to read on EtoBox.

What is Effect of Intensive vs Moderate Alveolar Recruitment Strategies Added to Lung-Protective Ventilation on Postoperative Pulmonary Complications: A Randomized Clinical Trial about?

## Importance: Perioperative lung-protective ventilation has been recommended to reduce pulmonary complications after cardiac surgery. the protective role of a small tidal volume (vt) has been established, whereas the added protection afforded by alveolar recruiting strategies remains controversial. ## Objective: To determine whether an intensive alveolar recruitment strategy could reduce postoperative pulmonary complications, when added to a protective ventilation with small vt. ## Design, setting, and participants: Randomized clinical trial of patients with hypoxemia after cardiac surgery at a single icu in brazil (december 2011-2014). ## Interventions: Intensive recruitment strategy (n=157) or moderate recruitment strategy (n=163) plus protective ventilation with small vt. ## Main outcomes and measures: Severity of postoperative pulmonary complications computed until hospital discharge, analyzed with a common odds ratio (or) to detect ordinal shift in distribution of pulmonary complication severity score (0-to-5 scale, 0, no complications; 5, death). prespecified secondary outcomes were length of stay in the icu and hospital, incidence of barotrauma, and hospital mortality. ## R

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Author

Alcino Costa Leme; Ludhmila Abrahao Hajjar; Marcia S. Volpe; Julia Tizue Fukushima; Roberta Ribeiro De Santis Santiago; Eduardo A. Osawa; Juliano Pinheiro de Almeida; Aline Muller Gerent; Rafael Alves Franco; Maria Ignez Zanetti Feltrim; Emília Nozawa; Vera Regina de Moraes Coimbra; Rafael de Moraes Ianotti; Clarice Shiguemi Hashizume; Roberto Kalil Filho; Jose Otavio Costa Auler; Fabio Biscegli Jatene; Filomena Regina Barbosa Gomes Galas; Marcelo Britto Passos Amato

Publisher

American Medical Association (AMA)

Published

2017

Language

EN

Field

Medicine (Health Sciences)