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DRESS syndrome: case report A 38-year-old woman developed drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome during treatment with propylthiouracil for hyperthyroidism [route and duration of treatment to reaction onset not stated]. The woman presented with nausea, erythroderma and fever. She was allergic to sulfonamides. She had a history of hyperthyroidism. She started receiving treatment with methimazole and propranolol on 28 May 2021. Her methimazole treatment was discontinued. She exhibited elevated liver transaminase [aetiology not stated]. Later, her liver functions returned to normal and she started receiving treatment with propylthiouracil 200 mg/day on 8 July 2021. However, she developed diffuse erythematous rash and nausea. Therefore, the woman's propylthiouracil was discontinued on 9 August 2021. Her erythema had spread to the chest and distal extremities, and she was hospitalised 10 days later. She had high fever, sinus tachycardia, diffuse erythema, submandibular lymphadenopathy and facial oedema. She also had increased leukocytes, absolute eosinophilia, atypical leukocytosis and abnormal liver function. Later, she was diagnosed with propylthiouraci

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Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Medicine (Health Sciences)