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Paracetamol is a slightly water soluble drug belongs to BCS Class IV, used in various pain managements & in management of fever. The drug solubility was increased by solid dispersion method, in which two techniques namely physical mixing and co-grinding were tried at the ratios of 1:0.25, 1:0.5 & 1:0.75 for paracetamol to oats powder. Various parameters like pre & post compressional parameters were tested and final formula was selected based on disintegration time and in-vitro dissolution profile. Where, al

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inventionjournals

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EN