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The document presents a study on the structures, dynamics, and functions of chromosomes, focusing on a Landscape Switching Model to address challenges in measuring 4D chromosome dynamics. It identifies distinct cell state transitions, particularly the transdifferentiation between Glia and Neuron cells, and discusses the mechanisms behind the formation of Topologically Associating Domains (TADs) and compartments. The research is conducted by Cibo Feng under the guidance of Prof. Xiakun Chu at the Hong Kong U

Author

cbfengphy

Language

EN