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A Decision Analysis of Thrombolytic Therapy Compared with Standard Therapy in Acute Ischaemic Stroke by S. Hallan; A. Åsberg; B. Indredavik; T. E. Widerøe is a Medicine article available to read on EtoBox.

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Abstract. Hallan S, Åsberg A, Indredavik B, Widerøe TE (University Hospital of Trondheim, Trondheim, Norway). A decision analysis of thrombolytic therapy compared with standard therapy in acute ischaemic stroke. __J Intern Med__ 1999; 246: 549–559. Objectives. Experts draw different conclusions on whether thrombolysis can be recommended or not for acute ischaemic stroke. A major problem is weighing the improvement in functional ability against the risk of increased mortality. We wanted to examine this uncertainty regarding thrombolysis using a systematic approach and with a strong emphasis on the patient’s point of view. Methods. We performed a decision analysis where the base case focused on an average stroke patient. We used published probabilities for different functional outcomes after standard supportive care and after adding tissue plasminogen activator (tPA), and we tried to estimate corresponding long‐term survival. We interviewed 158 subjects with the standard gamble method to elicit their preference values (utility) for these outcomes. Results. When using the baseline data for an average stroke patient, thrombolysis with tPA was the better choice, with 48 extra quality‐ad

Who reads A Decision Analysis of Thrombolytic Therapy Compared with Standard Therapy in Acute Ischaemic Stroke?

Author

S. Hallan; A. Åsberg; B. Indredavik; T. E. Widerøe

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0954-6820)

Published

1999

Language

EN

Field

Medicine (Health Sciences)