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What is Z-Selective Hydroalkylation of Alkynes about?

This document discusses a novel method for the selective synthesis of Z-Michael acceptors through the hydroalkylation of conjugated alkynes using silver catalysts and alkyl boranes. The developed reaction achieves high Z-selectivity and tolerates a variety of functional groups, facilitating the synthesis of α,β-unsaturated carbonyls which are valuable in synthetic and biological applications. The study highlights the unique reactivity of conjugated alkynes and expands the scope of hydroalkylation methods fo

Author

1341835113

Language

EN