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Pretreatment factors significantly influence quality of life in cancer patients: A Radiation Therapy Oncology Group (RTOG) analysis by Benjamin Movsas; Charles Scott; Deborah Watkins-Bruner is a Medicine article available to read on EtoBox.

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## Purpose: The purpose of this analysis was to assess the impact of pretreatment factors on quality of life (qol) in cancer patients. ## Methods and materials: Pretreatment qol (via functional assessment of cancer therapy [fact], version 2) was obtained in 1,428 patients in several prospective radiation therapy oncology group (rtog) trials including nonmetastatic head-and-neck (n = 1139), esophageal (n = 174), lung (n = 51), rectal (n = 47), and prostate (n = 17) cancer patients. clinically meaningful differences between groups were defined as a difference of 1 standard error of measurement (sem). ## Results: The mean fact score for all patients was 86 (20.7-112) with sem of 5.3. statistically significant differences in qol were observed based on age, race, karnofsky performance status, marital status, education level, income level, and employment status, but not by gender or primary site. using the sem, there were clinically meaningful differences between patients /=65 years. hispanics had worse qol than whites. fact increased linearly with higher karnofsky performance status and income levels. married patients (or live-in relationships) had a better qol than single, divorced, or

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Author

Benjamin Movsas; Charles Scott; Deborah Watkins-Bruner

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2006

Language

EN

Field

Medicine (Health Sciences)