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Pregnancy-associated lymphomas: A clinicopathologic study by Arnold B. Gelb; Matthijs van de Rijn; Roger A. Warnke; Onsi W. Kamel is a Medicine article available to read on EtoBox.

What is Pregnancy-associated lymphomas: A clinicopathologic study about?

## BACKGROUND. The natural histories of Hodgkin's disease (HD) and non-Hodgkin's lymphomas (NHL) during pregnancy are not well understood. METHODS. All cases of HD and NHL diagnosed during pregnancy at Stanford University Medical Center since 1987 were reviewed and clinical follow-up was obtained. Various immunohistochemical studies and in situ hybridization for Epstein-Barr virus (EBV) encoded RNA were performed in a subset of cases. ## RESULTS. Seventeen cases of HD and 12 cases of NHL were accessioned (median age; 27 yrs). The HD cases were classified as 13 nodular sclerosis type, 3 mixed cellularity type, and 1 unclassified. Clinical follow-up revealed most of the patients had Stage I1 to 111 disease and were diagnosed on average at 22 weeks gestation. Most of the patients deferred therapy until after delivery and had no evidence of disease at the last follow-up except for one death with disease but not from it. NHL were classified according to the working formulation as high or intermediate grade lymphomas of various types, including both nodal and extranodal sites. Clinical follow-up revealed most had Stage I1 to IV disease and were diagnosed on average at 23 weeks gestation.

Who reads Pregnancy-associated lymphomas: A clinicopathologic study?

Author

Arnold B. Gelb; Matthijs van de Rijn; Roger A. Warnke; Onsi W. Kamel

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1996

Language

EN

Field

Medicine (Health Sciences)