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Mode of Delivery After Labor Induction with Vaginal Dinoprostone Versus Oral Misoprostol for Women with Unfavorable Cervix at Term by Solène Jolivet; Mélanie Delavallade; Antoine Giraud; Céline Chauleur; Tiphaine Raia-Barjat is a Medicine article available to read on EtoBox.
What is Mode of Delivery After Labor Induction with Vaginal Dinoprostone Versus Oral Misoprostol for Women with Unfavorable Cervix at Term about?
Objective To compare the delivery mode after labor induction with 10 mg vaginal dinoprostone insert versus oral misoprostol 50 μg/4 h for women with an unfavorable cervix. Material and methods This is a retrospective observational study comparing the before/after introduction of oral misoprostol for labor induction, conducted at the Saint-Étienne University Hospital on a cohort of 396 women with a Bishop score <6. One hundred and twelve women (28.3%) were treated with a 10 mg vaginal dinoprostone insert versus 284 (71.7%) with oral misoprostol 50 μg/4 h. The primary outcome was the cesarean section rate. Results Labor induction with vaginal dinoprostone was independently associated with an increased rate of cesarean sections compared to oral misoprostol (aOR = 2.44; CI95% from 1.35 to 4.40; p = 0.003). The use of vaginal dinoprostone increased the induction rate during more than 48 h (18.8% versus 9.9%; p = 0.02), and the occurrence of fetal heart rate changes (34.8% versus 21.1%; p = 0.005). The maternofetal morbidity was similar. Conclusion Labor induction with vaginal dinoprostone was independently associated with an increased rate of cesarean sections compared to oral misoprost
Who reads Mode of Delivery After Labor Induction with Vaginal Dinoprostone Versus Oral Misoprostol for Women with Unfavorable Cervix at Term?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Solène Jolivet; Mélanie Delavallade; Antoine Giraud; Céline Chauleur; Tiphaine Raia-Barjat
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)