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Ciba Foundation Symposium - Bone Structure and Metabolism (Ciba/Bone) by Wolstenholme, G. E. W.; O'Connor, Cecilia M. is a Medicine article available to read on EtoBox.
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THE main purpose of this study has been to take advantage of isotope techniques to obtain a better knowledge of the histological remodelling of the adult bone. Furthermore, it was hoped that the research would provide some information on bone matrix. ## Compact bone in the dog Microradiography has certainly been one of the most useful tools in recent studies on compact bone (Engstrom, 1949; Amprino, 1952; Amprino and Engstrom, 1952). The pictures provided by this method are now familiar to all of us. They prove that calcification of compact bone occurs in two stages. At first, about three quarters of what will be the final load of calcium is stored by the osteon (Haversian system) while it is built up. Then, after ostcogenesis has ceased, calcification of the ostcon is slowly completed. The microradiograph docs not tell the whole story of the formation of an osteon. I n fact, calcification begins in a layer which already existed some time before. The information is obtained by comparing the microradiograph with the histological picture (Fig. ). Two concentric zones may be observed in an osteon which is being laid down. The inner zone is seen only with the microscope (long arrow of
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- Author
- Wolstenholme, G. E. W.; O'Connor, Cecilia M.
- Publisher
- John Wiley & Sons, Ltd.
- Published
- 2008
- Language
- EN
- ISBN
- 9780470714911
- Field
- Medicine (Life Sciences)
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