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Can I read Shenlingcao oral liquid for patients with non-small cell lung cancer receiving adjuvant chemotherapy after radical resection: A multicenter randomized controlled trial on EtoBox?
Shenlingcao oral liquid for patients with non-small cell lung cancer receiving adjuvant chemotherapy after radical resection: A multicenter randomized controlled trial by Yanmei Liu; Xiaochao Luo; Jiali Liu; Yu Ma; Jing Tan; Wen Wang; Jian Hu; Xiangning Fu; Lin Xu; Fenglei Yu; Shidong Xu; Haitao Ma; Xiuyi Yu; Qingjun You; Zhiqiang Wang; Ling Li; Xun Zhang; Xin Sun is a Medicine article available to read on EtoBox.
What is Shenlingcao oral liquid for patients with non-small cell lung cancer receiving adjuvant chemotherapy after radical resection: A multicenter randomized controlled trial about?
Background Low quality of life (QoL) in patients with non-small cell lung cancer (NSCLC) receiving adjuvant chemotherapy after radical resection is a major global health issue. High-quality evidence for the effectiveness of Shenlingcao oral liquid (SOL) as a complementary treatment in this patients is lacking at present. Purpose To determine whether complementary SOL treatment in NSCLC patients receiving adjuvant chemotherapy would yield greater improvements in QoL than chemotherapy alone. Study design We conducted a multicenter, randomized controlled trial of stages IIA-IIIA NSCLC patients undergoing adjuvant chemotherapy in seven hospitals. Methods Using stratified blocks, participants were randomized in a 1:1 ratio to receive SOL combined with conventional chemotherapy or conventional chemotherapy alone. The primary outcome was the change in global QoL from baseline to the fourth chemotherapy cycle, and intention-to-treat analysis was applied with a mixed-effect model. Secondary outcomes were functional QoL, symptoms, and performance status scores at the 6-month follow-up. Missing data were handled with multiple imputation and a pattern-mixture model. Results Among 516 randomize
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- Author
- Yanmei Liu; Xiaochao Luo; Jiali Liu; Yu Ma; Jing Tan; Wen Wang; Jian Hu; Xiangning Fu; Lin Xu; Fenglei Yu; Shidong Xu; Haitao Ma; Xiuyi Yu; Qingjun You; Zhiqiang Wang; Ling Li; Xun Zhang; Xin Sun
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Life Sciences)