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Ginsenoside Rh2 Efficacy in T-ALL Treatment by Nikoletta Aslanidi is a document available to read on EtoBox.
What is Ginsenoside Rh2 Efficacy in T-ALL Treatment about?
The document discusses how 20(S)-Ginsenoside Rh2 displays efficacy against T-cell acute lymphoblastic leukemia through inhibiting the PI3K/Akt/mTOR signaling pathway. It is found to decrease cell growth, arrest cell cycle, induce apoptosis and autophagy in leukemia cells by suppressing this pathway. In animal tests, 20(S)-Ginsenoside Rh2 alleviates leukemia symptoms and reduces white blood cells and CD3 staining in the spleen, demonstrating antitumor effects against T-ALL in vivo.
- Author
- Nikoletta Aslanidi
- Language
- EN