Can I read Synthesis of leucascandrolide A on EtoBox?

Synthesis of leucascandrolide A by Ying Wang; Jelena Janjic; Sergey A. Kozmin is a Chemistry article available to read on EtoBox.

What is Synthesis of leucascandrolide A about?

## Abstract This paper describes a convergent and stereocontrolled synthesis of leucascandrolide A, a marine natural product that exhibits potent growth inhibition of mammalian and yeast cells. The approach features a substrate-directed relay of the stereochemical information via a series of highly diastereoselective transformations. Spontaneous macrolactolization discovered during this synthetic exercise has provided an unprecedented access to this marine macrolide and demonstrates a new tactic for assembling large-ring systems based on the thermodynamic preference of hemiacetalization.

Who reads Synthesis of leucascandrolide A?

Author

Ying Wang; Jelena Janjic; Sergey A. Kozmin

Publisher

Walter de Gruyter GmbH

Published

2005

Language

EN

Field

Chemistry (Physical Sciences)